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Nicotine metabolism principally requires area within the liver. Consequently, when nicotine is administered through the GI program, it undergoes 1st-go metabolism through the liver, resulting in a bioavailability of only about 20%. This process inherently decreases the bioavailability of nicotine throughout the method and could trigger adverse GI effects. As https://juliuszqgwn.blogchaat.com/26774676/how-utbar-6000-puffs-5-nicotine-can-save-you-time-stress-and-money

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